Ion Chromatography (IC)

Ion Chromatography (IC) is the separation and quantification of anions and cations using High Performance Liquid Chromatography (HPLC). HPLC is an analytical technique based on the separation of the components of a mixture in solution by selective adsorption. There are basically three modes of separation: liquid/liquid, liquid/solid, and molecular size. Once the components have been separated, they are measured by a conductivity detector.

Standard solutions provide specific retention times for each ion and allow the creation of calibration curves for quantifying each species.

Details of Ion Chromatography

Residual Chlorine on a Medical Device

Analysis of Circuit Boards to Determine the Cause of Shorts

Cleaning Validation of Plastic Components

• Identify and quantify ionic species

  in a solution or an extract of a

  solid

• Anions Include:

  Fluorine, Chlorine, Nitrite,

  Bromine, Nitrate, Phosphate and

  Sulfate

• Cations Include:

  Lithium, Sodium, Ammonium,

  Potassium, Magnesium and

  Calcium

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